Fare Guide
Estimated lowest fares found within 7 days
Cheapest Airline
The cheapest airline(s) flying from Des Moines to Knoxville is Delta Air Lines.
Cheapest Month
July
Travel Period: May 2024 - April 2025
The cheapest month(s) to fly from Des Moines to Knoxville is July.
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May 2024
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Jun 2024
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Jul 2024
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Aug 2024
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Sep 2024
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Oct 2024
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Nov 2024
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Dec 2024
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Jan 2025
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Feb 2025
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Mar 2025
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Apr 2025
Cheapest Day of the Week
Tuesday
The cheapest day(s) of the week to fly from Des Moines to Knoxville is Tuesday.
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Sun Sunday
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Mon Monday
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Tue Tuesday
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Wed Wednesday
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Thu Thursday
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Fri Friday
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Sat Saturday
Cheapest Time
6am
The cheapest time of the day to fly from Des Moines to Knoxville is in the early morning.
Early Morning 12:01am - 06:00am
Morning 6:01am - 12:00pm
Afternoon 12:01pm - 6:00pm
Evening 6:01pm to 12:00am
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6am
12pm
6pm
Flight Schedules
Last Updated: Tue, 2 Apr, 2024
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Connecting Flights
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05:55 - 09:04DSM - ATL12:15 - 13:06ATL - TYS
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05:55 (DSM)Des Moines Airport12:15 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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09:04 (ATL)Atlanta Hartsfield-Jackson Intl Airport13:06 (TYS)Knoxville Airport
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Delta Air Lines (DL 1025)Boeing 717 Delta Air Lines (DL 2534)Boeing 717 - 06h 11m (03h 11m)
- ATL Atlanta 03h 11m
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05:58 - 07:24DSM - ORD08:18 - 11:03ORD - TYS
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05:58 (DSM)Des Moines Airport08:18 (ORD)Chicago O'Hare International Airport
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07:24 (ORD)Chicago O'Hare International Airport11:03 (TYS)Knoxville Airport
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American Airlines (AA 775)Boeing 737 800 American Airlines (AA 6019)Crj Canadair Regional - 04h 05m (00h 54m)
- ORD Chicago 00h 54m
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06:04 - 08:30DSM - IAH10:09 - 13:28IAH - TYS
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06:04 (DSM)Des Moines Airport10:09 (IAH)Houston George Bush Intercontinental Airport
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08:30 (IAH)Houston George Bush Intercontinental Airport13:28 (TYS)Knoxville Airport
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United Airlines (UA 1676)Airbus United Airlines (UA 4887)Embraer - 06h 24m (01h 39m)
- IAH Houston 01h 39m
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06:30 - 09:47DSM - CLT11:01 - 12:10CLT - TYS
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06:30 (DSM)Des Moines Airport11:01 (CLT)Charlotte Airport
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09:47 (CLT)Charlotte Airport12:10 (TYS)Knoxville Airport
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American Airlines (AA 2488)Airbus American Airlines (AA 5643)Canadair Regional - 04h 40m (01h 14m)
- CLT Charlotte 01h 14m
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06:30 - 09:47DSM - CLT13:05 - 14:14CLT - TYS
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06:30 (DSM)Des Moines Airport13:05 (CLT)Charlotte Airport
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09:47 (CLT)Charlotte Airport14:14 (TYS)Knoxville Airport
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American Airlines (AA 2488)Airbus American Airlines (AA 5579)Canadair Regional - 06h 44m (03h 18m)
- CLT Charlotte 03h 18m
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06:30 - 09:47DSM - CLT13:05 - 14:14CLT - TYS
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06:30 (DSM)Des Moines Airport13:05 (CLT)Charlotte Airport
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09:47 (CLT)Charlotte Airport14:14 (TYS)Knoxville Airport
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American Airlines (AA 2488)Airbus American Airlines (AA 5579)Canadair Regional - 06h 44m (03h 18m)
- CLT Charlotte 03h 18m
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06:30 - 09:47DSM - CLT13:06 - 14:15CLT - TYS
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06:30 (DSM)Des Moines Airport13:06 (CLT)Charlotte Airport
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09:47 (CLT)Charlotte Airport14:15 (TYS)Knoxville Airport
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American Airlines (AA 2488)Airbus American Airlines (AA 5579)Canadair Regional - 06h 45m (03h 19m)
- CLT Charlotte 03h 19m
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06:30 - 09:47DSM - CLT11:01 - 12:10CLT - TYS
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06:30 (DSM)Des Moines Airport11:01 (CLT)Charlotte Airport
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09:47 (CLT)Charlotte Airport12:10 (TYS)Knoxville Airport
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American Airlines (AA 2488)Airbus American Airlines (AA 5643)Canadair Regional - 04h 40m (01h 14m)
- CLT Charlotte 01h 14m
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08:00 - 09:26DSM - ORD10:35 - 13:23ORD - TYS
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08:00 (DSM)Des Moines Airport10:35 (ORD)Chicago O'Hare International Airport
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09:26 (ORD)Chicago O'Hare International Airport13:23 (TYS)Knoxville Airport
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United Airlines (UA 1391)Boeing 737 700 United Airlines (UA 5358)Crj Canadair Regional - 04h 23m (01h 09m)
- ORD Chicago 01h 09m
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08:00 - 09:26DSM - ORD10:35 - 13:23ORD - TYS
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08:00 (DSM)Des Moines Airport10:35 (ORD)Chicago O'Hare International Airport
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09:26 (ORD)Chicago O'Hare International Airport13:23 (TYS)Knoxville Airport
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United Airlines (UA 1391)Airbus United Airlines (UA 5358)Crj Canadair Regional - 04h 23m (01h 09m)
- ORD Chicago 01h 09m
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08:00 - 09:26DSM - ORD10:35 - 13:23ORD - TYS
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08:00 (DSM)Des Moines Airport10:35 (ORD)Chicago O'Hare International Airport
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09:26 (ORD)Chicago O'Hare International Airport13:23 (TYS)Knoxville Airport
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United Airlines (UA 1391)Boeing 737 800 United Airlines (UA 5358)Crj Canadair Regional - 04h 23m (01h 09m)
- ORD Chicago 01h 09m
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08:00 - 09:26DSM - ORD10:35 - 13:23ORD - TYS
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08:00 (DSM)Des Moines Airport10:35 (ORD)Chicago O'Hare International Airport
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09:26 (ORD)Chicago O'Hare International Airport13:23 (TYS)Knoxville Airport
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United Airlines (UA 1391)Boeing 737 900 United Airlines (UA 5358)Crj Canadair Regional - 04h 23m (01h 09m)
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11:37 - 13:08DSM - ORD14:10 - 16:58ORD - TYS
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11:37 (DSM)Des Moines Airport14:10 (ORD)Chicago O'Hare International Airport
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13:08 (ORD)Chicago O'Hare International Airport16:58 (TYS)Knoxville Airport
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United Airlines (UA 3591)Embraer 170 United Airlines (UA 5379)Crj Canadair Regional - 04h 21m (01h 02m)
- ORD Chicago 01h 02m
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11:43 - 13:49DSM - DFW14:29 - 17:35DFW - TYS
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11:43 (DSM)Des Moines Airport14:29 (DFW)Dallas/Fort Worth Intl Airport
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13:49 (DFW)Dallas/Fort Worth Intl Airport17:35 (TYS)Knoxville Airport
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American Airlines (AA 1536)Airbus American Airlines (AA 2542)Boeing 737 800 - 04h 52m (00h 40m)
- DFW Dallas 00h 40m
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11:56 - 13:22DSM - ORD15:31 - 18:07ORD - TYS
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11:56 (DSM)Des Moines Airport15:31 (ORD)Chicago O'Hare International Airport
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13:22 (ORD)Chicago O'Hare International Airport18:07 (TYS)Knoxville Airport
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American Airlines (AA 6057)Crj Canadair Regional American Airlines (AA 3397)Embraer 170 - 05h 11m (02h 09m)
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12:02 - 13:26DSM - ORD15:31 - 18:07ORD - TYS
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12:02 (DSM)Des Moines Airport15:31 (ORD)Chicago O'Hare International Airport
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13:26 (ORD)Chicago O'Hare International Airport18:07 (TYS)Knoxville Airport
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American Airlines (AA 3743)Embraer 170 American Airlines (AA 3397)Embraer 170 - 05h 05m (02h 05m)
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12:06 - 13:32DSM - ORD15:31 - 18:07ORD - TYS
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12:06 (DSM)Des Moines Airport15:31 (ORD)Chicago O'Hare International Airport
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13:32 (ORD)Chicago O'Hare International Airport18:07 (TYS)Knoxville Airport
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American Airlines (AA 6055)Crj Canadair Regional American Airlines (AA 3397)Embraer 170 - 05h 01m (01h 59m)
- ORD Chicago 01h 59m
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12:09 - 15:15DSM - ATL16:59 - 17:56ATL - TYS
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12:09 (DSM)Des Moines Airport16:59 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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15:15 (ATL)Atlanta Hartsfield-Jackson Intl Airport17:56 (TYS)Knoxville Airport
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Delta Air Lines (DL 1704)Boeing 717 Delta Air Lines (DL 5224)Canadair Regional - 04h 47m (01h 44m)
- ATL Atlanta 01h 44m
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12:09 - 15:15DSM - ATL16:59 - 17:52ATL - TYS
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12:09 (DSM)Des Moines Airport16:59 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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15:15 (ATL)Atlanta Hartsfield-Jackson Intl Airport17:52 (TYS)Knoxville Airport
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Delta Air Lines (DL 1704)Boeing 717 Delta Air Lines (DL 1629)Airbus - 04h 43m (01h 44m)
- ATL Atlanta 01h 44m
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12:09 - 15:15DSM - ATL18:38 - 19:35ATL - TYS
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12:09 (DSM)Des Moines Airport18:38 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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15:15 (ATL)Atlanta Hartsfield-Jackson Intl Airport19:35 (TYS)Knoxville Airport
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Delta Air Lines (DL 1704)Boeing 717 Delta Air Lines (DL 5203)Canadair Regional - 06h 26m (03h 23m)
- ATL Atlanta 03h 23m
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12:09 - 15:15DSM - ATL18:38 - 19:35ATL - TYS
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12:09 (DSM)Des Moines Airport18:38 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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15:15 (ATL)Atlanta Hartsfield-Jackson Intl Airport19:35 (TYS)Knoxville Airport
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Delta Air Lines (DL 1704)Boeing 717 Delta Air Lines (DL 5203)Crj 700 Canadair Regional - 06h 26m (03h 23m)
- ATL Atlanta 03h 23m
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12:09 - 15:15DSM - ATL18:00 - 18:57ATL - TYS
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12:09 (DSM)Des Moines Airport18:00 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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15:15 (ATL)Atlanta Hartsfield-Jackson Intl Airport18:57 (TYS)Knoxville Airport
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Delta Air Lines (DL 1704)Boeing 717 Delta Air Lines (DL 5203)Canadair Regional - 05h 48m (02h 45m)
- ATL Atlanta 02h 45m
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13:00 - 16:17DSM - CLT18:30 - 19:40CLT - TYS
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13:00 (DSM)Des Moines Airport18:30 (CLT)Charlotte Airport
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16:17 (CLT)Charlotte Airport19:40 (TYS)Knoxville Airport
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American Airlines (AA 2962)Airbus American Airlines (AA 5206)Canadair Regional - 05h 40m (02h 13m)
- CLT Charlotte 02h 13m
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14:11 - 17:47DSM - LGA18:32 - 20:51LGA - TYS
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14:11 (DSM)Des Moines Airport18:32 (LGA)New York La Guardia Airport
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17:47 (LGA)New York La Guardia Airport20:51 (TYS)Knoxville Airport
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Delta Air Lines (DL 4916)Canadair Regional Delta Air Lines (DL 5003)Canadair Regional - 05h 40m (00h 45m)
- LGA New York City 00h 45m
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14:56 - 17:25DSM - IAH19:50 - 23:05IAH - TYS
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14:56 (DSM)Des Moines Airport19:50 (IAH)Houston George Bush Intercontinental Airport
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17:25 (IAH)Houston George Bush Intercontinental Airport23:05 (TYS)Knoxville Airport
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United Airlines (UA 5333)Embraer 175 United Airlines (UA 4810)Embraer - 07h 09m (02h 25m)
- IAH Houston 02h 25m
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15:25 - 16:56DSM - ORD18:15 - 21:12ORD - TYS
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15:25 (DSM)Des Moines Airport18:15 (ORD)Chicago O'Hare International Airport
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16:56 (ORD)Chicago O'Hare International Airport21:12 (TYS)Knoxville Airport
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United Airlines (UA 4693)Embraer 175 United Airlines (UA 5420)Crj Canadair Regional - 04h 47m (01h 19m)
- ORD Chicago 01h 19m
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15:25 - 16:56DSM - ORD18:15 - 21:12ORD - TYS
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16:56 (ORD)Chicago O'Hare International Airport21:12 (TYS)Knoxville Airport
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United Airlines (UA 3467)Embraer 175 United Airlines (UA 5420)Crj Canadair Regional - 04h 47m (01h 19m)
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17:10 - 19:59DSM - DTW20:35 - 22:10DTW - TYS
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17:10 (DSM)Des Moines Airport20:35 (DTW)Detroit Wayne County
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19:59 (DTW)Detroit Wayne County22:10 (TYS)Knoxville Airport
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Delta Air Lines (DL 5352)Canadair Regional Delta Air Lines (DL 5054)Canadair Regional - 04h 00m (00h 36m)
- DTW Detroit 00h 36m
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17:43 - 19:46DSM - DFW20:54 - 23:59DFW - TYS
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17:43 (DSM)Des Moines Airport20:54 (DFW)Dallas/Fort Worth Intl Airport
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19:46 (DFW)Dallas/Fort Worth Intl Airport23:59 (TYS)Knoxville Airport
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American Airlines (AA 2229)Boeing 737 800 American Airlines (AA 1052)Airbus - 05h 16m (01h 08m)
- DFW Dallas 01h 08m
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18:09 - 21:18DSM - ATL23:00 - 23:55ATL - TYS
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18:09 (DSM)Des Moines Airport23:00 (ATL)Atlanta Hartsfield-Jackson Intl Airport
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21:18 (ATL)Atlanta Hartsfield-Jackson Intl Airport23:55 (TYS)Knoxville Airport
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Delta Air Lines (DL 2086)Boeing 717 Delta Air Lines (DL 1687)Boeing 737 900 - 04h 46m (01h 42m)
- ATL Atlanta 01h 42m
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18:09 - 21:18DSM - ATL22:54 - 23:48ATL - TYS
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21:18 (ATL)Atlanta Hartsfield-Jackson Intl Airport23:48 (TYS)Knoxville Airport
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Delta Air Lines (DL 2086)Boeing 717 Delta Air Lines (DL 1687)Boeing 737 900 - 04h 39m (01h 36m)
- ATL Atlanta 01h 36m
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How far is Knoxville from Des Moines?
The flight distance between Des Moines and Knoxville is 1047km. Check all available flights on Wego.
When is the earliest and latest flight of the day?
The earliest flight of the day departs at 10:55. The last flight of the day departs at 23:09. See the full list of flight times on Wego.
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